Peer-reviewed veterinary case report
Changes in the blood lipid-transporting system in rats over the first day of experimental peritonitis.
- Journal:
- Bulletin of experimental biology and medicine
- Year:
- 2004
- Authors:
- Osochuk, S S & Konevalova, N Yu
- Affiliation:
- Department of General and Clinical Biochemistry
- Species:
- rodent
Abstract
Changes in the lipid spectrum of blood plasma and composition of high-density lipoproteins in outbred albino rats were studied during early stages of experimental peritonitis. We revealed an increase in lecithin:cholesterol acyltransferase activity, activation of lipolytic production of high-density lipoproteins from very-low-density lipoproteins, and substitution of arachidonic acid in cholesterol esters for dihomo-gamma-linoleic acid 7 h after induction of peritonitis. After 24 h the protein composition and functional activity of high-density lipoproteins was modified and the amount of saturated fatty acids in cholesterol esters increased.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/15723123/