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Peer-reviewed veterinary case report

Kidneys filter less in hyperthyroid cats after radioactive iodine

By Boag, A K et al.·Published in The Veterinary record·2007·Department of Veterinary Clinical Science, United Kingdom·View original on PubMed

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Original publication title: Changes in the glomerular filtration rate of 27 cats with hyperthyroidism after treatment with radioactive iodine.

Species:
cat

Plain-English summary

A group of 27 older cats with hyperthyroidism (an overactive thyroid) were treated with radioactive iodine to help manage their condition. After treatment, the cats showed a decrease in kidney function, as measured by their glomerular filtration rate (GFR), one month later, and this lower level remained stable for the next five months. The only factor that seemed to predict a significant decline in kidney function was the cats' blood sugar levels before treatment. It's important for pet owners to monitor their cats' kidney health after hyperthyroidism treatment, as changes can occur.

People also search for: cat hyperthyroidism treatment · cat kidney function after iodine therapy · older cat kidney health monitoring

Abstract

Hyperthyroidism is a common endocrinopathy of older cats and is associated with an increased glomerular filtration rate (gfr). Renal dysfunction is also common in older cats and may develop after they have been treated for hyperthyroidism. This paper describes the changes in the gfr of 27 hyperthyroid cats in the six months after their treatment with radioactive iodine ((131)I), and evaluates whether any commonly measured pretreatment parameters (serum biochemistry, systolic blood pressure, urine specific gravity) could predict a clinically significant decline in renal function. The gfr of all the cats had decreased one month after treatment, and the mean gfr was significantly lower. There was no further significant change in gfr between one and six months. The only independent variable associated with the final gfr was the pretreatment plasma glucose concentration (P=0.003).

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/18037692/