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Peer-reviewed veterinary case report

Characterization and clinical application of mesenchymal stem cells from equine umbilical cord blood.

Journal:
Journal of veterinary science
Year:
2013
Authors:
Kang, Jun-Gu et al.
Affiliation:
Department of Veterinary Internal Medicine · South Korea
Species:
horse

Abstract

Tendinitis of the superficial digital flexor tendon (SDFT) is a significant cause of lameness in horses; however, recent studies have shown that stem cells could be useful in veterinary regenerative medicine. Therefore, we isolated and characterized equine umbilical cord blood mesenchymal stem cells (eUCB-MSCs) from equine umbilical cord blood obtained from thoroughbred mares during the foaling period. Horses that had tendinitis of the SDFT were treated with eUCB-MSCs to confirm the therapeutic effect. After eUCB-MSCs transplantation, the core lesion in the SDFT was found to decrease. These results suggest that transplantation using eUCB-MSCs could be another source of cell treatment.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/23820166/