Peer-reviewed veterinary case report
Carbapenemase-producing bacteria found in dogs' rectal swabs
By Cole, Stephen D & Rankin, Shelley C·Published in Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·2022·Department of Pathobiology, United States·View original on PubMed →
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Original publication title: Characterization of 2carbapenemase-producing Enterobacterales isolated from canine rectal swabs.
- Species:
- dog
Plain-English summary
A 6-year-old Yorkshire Terrier with a weakened immune system and a 3-year-old Labrador Retriever with sudden diarrhea were both found to have a type of bacteria called carbapenemase-producing Enterobacterales (CPE) that can cause serious infections. The Yorkshire Terrier's bacteria had specific genetic traits, while the Labrador's bacteria had additional genes that could produce toxins. This situation highlights the importance of understanding how these bacteria might spread in pets and the need for thorough testing in veterinary medicine. Further studies are needed to explore the role of pets in the spread of these infections.
People also search for: dog diarrhea treatment · Yorkshire Terrier immune system issues · carbapenemase-producing bacteria in pets
Abstract
Globally, carbapenemase-producing Enterobacterales (CPE) cause life-threatening, hospital-acquired infections in people, and have been reported recently among veterinary patients. Organisms that produce acarbapenemase (KPC) are one of the most common CPE isolated from people but have been reported only rarely in animals. We characterized 2 KPC-producing Enterobacterales isolated from companion animal rectal swabs during the response to an outbreak caused by a strain of. Both isolates were characterized by whole-genome sequencing (WGS) and analysis. The first isolate (case A) was from an immunosuppressed 6-y-old Yorkshire Terrier and was identified as(ST372) with agene and an IncFII plasmid. The second isolate (case B) was from a 3-y-old Labrador Retriever with acute diarrhea and was identified aswith agene, multiple plasmids (ColRNAI, pKPC-CAV1193), and a putative enterotoxin gene (). Further research is needed to determine what role animals might play in the epidemiology of CPE in communities. It is imperative that all CPE isolated from companion animals be fully characterized by WGS and the associated case examined. All veterinary isolates should be sequenced and shared for surveillance, monitoring, and investigation purposes.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/34931554/