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Peer-reviewed veterinary case report

Characterization of feline hereditary retinal dystrophies using clinical, functional, structural and molecular genetic studies.

Journal:
Veterinary ophthalmology
Year:
2011
Authors:
Narfström, Kristina et al.
Affiliation:
Department of Veterinary Medicine and Surgery · United States
Species:
cat

Abstract

Only in recent years have specific mutations been elucidated for feline hereditary retinal dystrophies. Molecular genetic characterization of feline diseases has so far been a slow process but with a full genome sequence for the cat recently completed and the development of a feline single nucleotide polymorphism chip, the characterization of feline monogenic disorders will be significantly simplified. This review summarizes current knowledge with regard to specific hereditary retinal dystrophies in cats and gives an overview of how cats can be used as models in translational research.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/21923821/