Peer-reviewed veterinary case report
Heart health before kidney transplant and survival in cats
By Aronson, Lillian et al.·Published in Journal of the American Veterinary Medical Association·2022·School of Veterinary Medicine, United States·View original on PubMed →
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Original publication title: Characterization of preoperative cardiovascular status and association with outcome following feline renal allograft transplantation: 166 cases.
- Species:
- cat
Plain-English summary
A group of 166 cats, mostly adult male domestic shorthairs, underwent kidney transplant surgery due to severe kidney disease. Before the surgery, their heart health was assessed, but issues like high blood pressure or heart murmurs did not affect their chances of surviving the surgery or living longer afterward. The only factor that significantly impacted survival was age; for each year older a cat was, the risk of death increased by 11%. This means that even if a cat has heart problems, it might still be a candidate for a transplant, but owners should be aware that older cats may have a higher risk after surgery.
People also search for: cat kidney transplant survival · heart problems in cats · age impact on cat surgery outcomes
Abstract
OBJECTIVES: To retrospectively evaluate preoperative historical, biochemical, and cardiovascular screening data for predictors of survival to discharge and long-term survival in feline renal allograft recipients from 1 institution. ANIMALS: 166 cats that underwent renal transplantation at the University of Pennsylvania between 1998 and 2018. PROCEDURES: Medical records were reviewed for preoperative historical information, biochemical data, and cardiac assessment including auscultation findings, pre- and postoperative systolic blood pressure measurements, thoracic radiographic evaluation, and echocardiographic measurements. The need for hemodialysis, the number of surgical procedures, native kidney biopsy diagnosis and survival time was also recorded. Kaplan-Meier analysis was used to generate survival plots and estimate median survival times with a 95% CI. Univariable and multivariable analysis were performed to determine variables that were independently associated with survival to discharge and long-term survival. RESULTS: The patient population primarily consisted of adult male DSH cats (70%) diagnosed with IRIS stage 4 CKD (66.3%). Abnormalities identified on preoperative cardiac assessment, including hypertension, the presence of a murmur, echocardiographic changes, and radiographic signs of congestive heart failure, were not associated with survival to discharge or long-term survival. Age was the only single significant variable associated with survival, and the risk of death increased by 11% (95% CI, 6% to 17%) for every 1 year in patient age. CLINICAL RELEVANCE: The presence of cardiac abnormalities identified during the screening process of cats presenting for transplantation should not immediately exclude a potential candidate for the procedure. Owners considering transplantation should be educated on the impact of age on survival following surgery.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/35905154/