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Peer-reviewed veterinary case report

Characterization of the full-length genomic sequences of vesicular stomatitis Cocal and Alagoas viruses.

Journal:
Archives of virology
Year:
2008
Authors:
Pauszek, Steven J et al.
Affiliation:
US Department of Agriculture · United States

Abstract

In Brazil and Argentina, vesicular stomatitis (VS) is caused by distinct viral strains serologically related to the classical vesicular stomatitis virus Indiana (VSIV), namely VS Indiana-2 (VSIV-2) and VS Indiana-3 (VSIV-3). Here we describe the full-length genomic sequences and organization of the prototype strains of VSIV-2 Cocal virus (COCV) and VSIV-3 Alagoas virus (VSAV). These viruses showed similar genomic organizations to VSIV field isolates except that the non-structural C'/C proteins, markedly conserved throughout the vesiculoviruses, were absent in VSAV. Phylogenetic analyses consistently grouped COCV, VSAV and VSIV in a monophyletic group distinct from VSNJV, supporting the classification of these viruses within the Indiana serogroup.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/18512001/