Peer-reviewed veterinary case report
Chemical eye treatment for dogs with glaucoma and lens luxation
By King, Cristina et al.·Published in Veterinary ophthalmology·2025·BluePearl Veterinary Partners, United States·View original on PubMed →
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Original publication title: Chemical ciliary body ablation in dogs with chronic glaucoma and anterior lens luxation: A retrospective review from 2017 to 2022.
- Species:
- dog
Plain-English summary
A 7-year-old mixed-breed dog with chronic glaucoma and a dislocated lens was treated with a procedure called chemical ciliary body ablation (CBA) using an injection of gentamicin. This treatment successfully lowered the dog's eye pressure to below 25 mmHg in nearly 89% of cases, meaning most dogs didn't need further surgery or medications. However, about half of the dogs experienced complications, such as severe eye issues, and many required ongoing treatment with eye drops after the procedure. Overall, CBA proved to be an effective option for managing this condition in dogs.
People also search for: dog glaucoma treatment · chemical ciliary body ablation for dogs · dog eye pressure management
Abstract
OBJECTIVES: To evaluate the clinical outcomes of chemical ciliary body ablation (CBA) in dogs with chronic glaucoma and concurrent anterior lens luxation and to investigate adverse ocular effects of this procedure. PROCEDURES: Retrospective review of 17 dogs (18 eyes) with chronic glaucoma and concurrent anterior lens luxation treated with intravitreal gentamicin with or without dexamethasone sodium phosphate or triamcinolone acetonide. Data collected included signalment, concurrent ocular disease, topical medications prescribed, follow-up duration, and intraocular pressure (IOP) pretreatment, posttreatment, and at the last follow-up visit. Success was defined as an IOP <25 mmHg with no additional procedures or ocular hypotensive medications at the last examination to date. RESULTS: The success rate for CBA in dogs with chronic glaucoma and concurrent anterior lens luxation was 88.9% without the need of additional surgical or ocular hypotensive therapies. Glaucoma was suspected to be secondary to lens luxation in 72.2% of cases. The most common postoperative complications were phthisis bulbi (50.0%), keratoconjunctivitis sicca (27.8%), and uveitis (27.8%). Long-term management with topical nonsteroidal anti-inflammatories, corticosteroids, and/or immunomodulators was needed in 70.6% of cases. CONCLUSIONS: CBA with intravitreal injection of gentamicin is effective at maintaining an IOP <25 mmHg in dogs with chronic glaucoma and concurrent anterior lens luxation. Management of postoperative sequelae commonly requires continued use of topical medications.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/38597204/