Peer-reviewed veterinary case report
Chemotherapy of leishmaniasis Part VI: synthesis and bioevaluation of some novel terpenyl S,N- and N,N-acetals.
- Journal:
- European journal of medicinal chemistry
- Year:
- 2007
- Authors:
- Suryawanshi, S N et al.
- Affiliation:
- Central Drug Research Institute · India
- Species:
- rodent
Abstract
Some novel terpene based oxoketene S,N-acetals 2(a-g) and N,N-acetals 3(a-c) have been synthesized from oxoketene dithioacetal 1. The compounds were screened for their in vivo antileishmanial activity. Some of the compounds showed 50-70% inhibition in the hamster model.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/17178176/