Peer-reviewed veterinary case report
Chlorpyrifos poisoning signs and treatment in two cats
By Jaggy, A & Oliver, J E·Published in Journal of veterinary internal medicine·1990·Department of Small Animal Medicine, United States·View original on PubMed →
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Original publication title: Chlorpyrifos toxicosis in two cats.
- Species:
- cat
Plain-English summary
Two cats were brought in showing signs of poisoning after being exposed to chlorpyrifos, a pesticide not recommended for use on cats. They had been experiencing chronic symptoms of organophosphate poisoning, which worsened after receiving diazepam, a sedative. The veterinarians treated them with a combination of pralidoxime chloride and atropine, which led to a dramatic improvement. After six injections, both cats made a full recovery and returned to their normal selves.
People also search for: cat pesticide poisoning symptoms · chlorpyrifos toxicity treatment · cat diazepam side effects
Abstract
Organophosphate compounds are widely employed for control of external parasites in cats and for control of insects in homes and yards. Chlorpyrifos is a long-acting organophosphate (OP) available for use as a systemically and topically acting parasiticide and insecticide in cattle. Its use on cats is not recommended, and no previous clinical cases of toxicosis have been described. Two cases of chronic chlorpyrifos toxicosis in cats are presented and pathophysiology as well as treatment are discussed. The cats had been showing signs of chronic organophosphate toxicosis before diazepam administration. Signs of acute organophosphate toxicosis were precipitated after diazepam was given. Treatment with pralidoxime chloride (2-PAM) and atropine was attempted. Response to treatment was dramatic and complete recovery was achieved with six injections of pralidoxime and atropine administration.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/1694899/