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Peer-reviewed veterinary case report

Dog with vomiting and jaundice diagnosed with cholangiohepatitis

By Forrester, S D et al.·Published in Journal of the American Veterinary Medical Association·1992·Department of Small Animal Clinical Sciences·View original on PubMed

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Original publication title: Cholangiohepatitis in a dog.

Species:
dog
Stomach & digestionDogs

Plain-English summary

A dog was brought to the vet after 4 days of not eating, vomiting, having a fever, and yellowing of the skin and eyes (icterus). The vet found that the dog was also depressed, dehydrated, and had an enlarged liver and spleen, along with abdominal pain. After surgery to take samples from the liver and bile, the vet discovered a bacterial infection called cholangiohepatitis. The dog was treated with fluids and an antibiotic called chloramphenicol, which helped it recover.

People also search for: dog vomiting and fever · dog jaundice treatment · cholangiohepatitis in dogs · dog liver infection symptoms

Abstract

Cholangiohepatitis was diagnosed in a dog with a 4-day history of anorexia, vomiting, fever, and icterus. Additional findings included signs of depression, dehydration, hepatosplenomegaly, and abdominal discomfort. Exploratory laparotomy was performed, and specimens of liver, spleen, and bile were obtained. Histologic evaluation of liver and spleen revealed acute, suppurative cholangio-hepatitis and splenitis, respectively. Cultures of liver and bile yielded Klebsiella sp. The dog responded to rehydration and intravenous administration of chloramphenicol. Although uncommon, cholangiohepatitis should be suspected in dogs with anorexia, fever, vomiting, icterus, and signs of abdominal discomfort. Definitive diagnosis requires bacterial cultures of liver and bile. Administration of an appropriate antibiotic should resolve clinical signs.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/1624352/