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Peer-reviewed veterinary case report

Dog with breathing trouble found to have cholesterol granuloma

By Davis, Anastacia Marie et al.·Published in Journal of the American Animal Hospital Association·2022·From the Virginia-Maryland College of Veterinary Medicine·View original on PubMed

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Original publication title: Cholesterol Granuloma of the Cranial Mediastinum in a Dog.

Species:
dog

Plain-English summary

A 10-year-old female spayed Pomeranian was brought in for coughing and trouble breathing. The vet found a mass in her chest that was initially thought to be a thymoma (a type of tumor), but after surgery, it turned out to be a cholesterol granuloma, which is a type of inflammatory lesion. Although she had some breathing difficulties a few days after the surgery, she received supportive care and improved. Five months later, follow-up X-rays showed no signs of the mass returning, and her breathing was normal again.

People also search for: Pomeranian coughing and breathing problems · cholesterol granuloma in dogs · dog surgery recovery breathing issues

Abstract

A 10 yr old female spayed Pomeranian presented with a history of dyspnea and coughing and was diagnosed with a cranial mediastinal mass presumed to be a thymoma. Surgical removal was elected and occurred without intraoperative complications. Histopathology revealed the lesion to be a cholesterol granuloma. The patient developed a brief period of increased respiratory difficulty 3 days postoperatively. Thoracic radiographs showed mild pleural effusion and the patient improved with supportive care. Five months postoperatively, repeat thoracic radiographs revealed no evidence of recurrence or respiratory pathology. This case report describes a cholesterol granuloma in a unique location and reviews the pathogenesis/pathophysiology of this type of mass.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/35576403/