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Peer-reviewed veterinary case report

Cholinergic pruritus in a horse.

Journal:
Journal of the American Veterinary Medical Association
Year:
1992
Authors:
Logas, D et al.
Affiliation:
Department of Small Animal Clinical Sciences · United States
Species:
horse

Plain-English summary

An 8-year-old male horse, known as a gelding, had been experiencing intense itching only after exercising for the past year. The condition was identified as cholinergic pruritus, which means he gets very itchy when his body temperature rises, but without the hives that sometimes accompany similar conditions in people. To help confirm the diagnosis, the veterinarians tested him by having him exercise and take hot-water baths to raise his body temperature. Unfortunately, there are no specific lab tests available to diagnose this condition. The treatment outcome is not mentioned, so it's unclear if any specific treatment was effective.

Abstract

An 8-year-old gelding, with a 1-year history of intense pruritus only after exercise, was diagnosed as having cholinergic pruritus. Provocative testing, using exercise and hot-water baths to increase core body temperature, assisted in the diagnosis. Cholinergic pruritus in human beings is a variant of the more common syndrome, cholinergic urticaria, which is characterized by intense pruritus and pinpoint urticaria. With cholinergic pruritus, intense itching results without urticaria. Specific diagnostic laboratory tests have not been developed.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/1644653/