Peer-reviewed veterinary case report
Chordoma of the sacrum of an adult naked mole-rat.
- Journal:
- Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc
- Year:
- 2020
- Authors:
- Cole, Jordan E et al.
- Affiliation:
- Smithsonian Conservation and Biology Institute · United States
- Species:
- rodent
Abstract
The naked mole-rat (NMR;)-a small, eusocial, subterranean rodent native to East Africa-is distinguished by its capability to live long and resist changes associated with the aging process. Notably, a growing amount of research has been dedicated to NMRs' multifactorial capacity to resist cancer. Since 2016, however, zoos have begun to document various neoplasms in a handful of individuals. We present herein radiographic, gross anatomic, and histopathologic features of a case of a sacral chordoma in a geriatric female. Chordomas originate in notochordal remnants. These spinal tumors are most commonly seen in ferrets; chordomas are rare in humans, can be difficult to treat, and need wide surgical margins.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/31838959/