Peer-reviewed veterinary case report
Dog with choroid plexus carcinoma causing head tilt and weight loss
By de Witt, Anika A. et al.·Published in Veterinary Record Case Reports·2022·Faculty of Veterinary Science University of Pretoria Onderstepoort Pretoria Gauteng South Africa·View original on Crossref →
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Original publication title: Choroid plexus carcinoma in a dog—Case report
- Species:
- dog
Plain-English summary
A 4-year-old Boerboel dog was brought in with a left head tilt, weight loss, depression, and slow heart rate. After running tests, including an MRI, the vet diagnosed the dog with a choroid plexus carcinoma, a type of brain tumor that can spread. The diagnosis was confirmed through a biopsy that showed signs of malignancy. Unfortunately, due to the aggressive nature of this cancer, treatment options may be limited, and the prognosis can be serious.
People also search for: dog head tilt · Boerboel brain tumor symptoms · choroid plexus carcinoma treatment
Abstract
Abstract Obtaining a conclusive definitive diagnosis for an intra‐ventricular tumour in a dog can be challenging. In doing so, all differential diagnoses should be considered. Differentiation between choroid plexus tumours (CPTs) (a choroid plexus papilloma, atypical choroid plexus papilloma or choroid plexus carcinoma) and gliomas, including ependymoma, oligodendroglioma and astrocytoma should be considered. Histopathologic features and immunohistochemistry are essential in the differentiation between intra‐ventricular tumours. A 4‐year‐old Boerboel dog presented with a left head tilt and a wide range of nonspecific clinical abnormalities not limited to weight loss, depression and marked bradycardia. MRI proved useful in providing a diagnosis of an intra‐ventricular tumour and demonstrated the potential of choroid plexus carcinomas (CPCs) to metastasize. In this case, the histological features displayed malignancy with invasion into the neuroparenchyma, drop metastasis and immunohistochemistry with E‐cadherin‐positive result that assisted with differentiation of CPC from other tumours.
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Search related cases →Original publication on Crossref: https://doi.org/10.1002/vrc2.403