Peer-reviewed veterinary case report
Chromium(III) complexes of D-glucosaminic acid and their effect on decreasing blood sugar in vivo.
- Journal:
- Archiv der Pharmazie
- Year:
- 2006
- Authors:
- Ou, Sheng-Ju et al.
- Affiliation:
- Coordination Chemistry Institute · China
- Species:
- rodent
Abstract
Two chromium(III) complexes of glucosaminic acid were synthesized by neutralization and exchange reaction. The formation of 1 : 1 and 2 : 3 (Cr : glucosaminate) complexes was confirmed by elemental analyses and spectroscopic studies. The effect of the complexes on decreasing blood sugar was investigated on type-2 diabetes model rats induced by tetraoxypyrimidine. The results indicated that the effect on decreasing blood sugar was comparable to that of picolinate chromium complex (Cr(pic)(3)) currently used world wide.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/16941731/