Peer-reviewed veterinary case report
Dog with kidney tumor causing blood in urine and weight loss
By Kobayashi, Naohito et al.·Published in Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·2010·Department of Molecular Pathology, Japan·View original on PubMed →
PetCaseFinder translated the abstract of this peer-reviewed paper into plain English so pet owners can read it. We do not publish original research — every detail traces back to the citation above. How we work →
Original publication title: Chromophobe renal cell carcinoma with sarcomatoid transformation in a dog.
- Species:
- dog
Plain-English summary
A 12-year-old spayed female Siberian husky was brought in because she was experiencing blood in her urine and losing weight. An ultrasound showed a large tumor in her left kidney, which was about 8 cm wide. The vet performed surgery to remove the kidney, and the tumor was found to have specific features similar to a type of kidney cancer seen in humans called chromophobe renal cell carcinoma. Unfortunately, the outcome details were not provided, but the diagnosis was confirmed through lab tests on the tumor.
People also search for: dog blood in urine · Siberian husky weight loss · kidney tumor surgery in dogs
Abstract
A 12-year-old spayed female Siberian husky dog presented with hematuria and weight loss. An abdominal ultrasonographic examination revealed a left renal tumor measuring 8 cm in diameter, and a nephrectomy was performed. The resected kidney contained a cavitated tumor with a white solid region. Histologically, this tumor was composed of large polygonal cells with abundant and cloudy cytoplasm and focal sarcomatoid change. The neoplastic epithelial cells were reactive with colloidal iron staining; Dolichos biflorus agglutinin, peanut agglutinin, and Ulex europaeus agglutinin I lectins; and cluster of differentiation 10 and c-KIT antigens but not for periodic acid-Schiff or vimentin stain. Neoplastic sarcomatoid cells stained positive for vimentin. Because these histopathologic features are identical to those of human chromophobe renal cell carcinoma, the present case was diagnosed as canine chromophobe renal cell carcinoma.
Find similar cases for your pet
PetCaseFinder finds other peer-reviewed reports of pets with the same symptoms, plus a plain-English summary of what was tried across them.
Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/21088189/