Chronic social stress differentially regulates neuroendocrine responses in laying hens: II. Genetic basis of adrenal responses under three different social conditions.

Abstract

Chicken lines were divergently selected for both high (HGPS) or low (LGPS) group productivity and survivability resulting from cannibalism and flightiness in colony cages. Each line has unique characteristics in physical indexes, domestic behavior, and physiological responsiveness to stress. The differences between the selected lines could be reflected in differing regulation of the neuroendocrine system such as the hypothalamic-pituitary-adrenal axis. Change of the adrenal function is a key initial event in response to stress in animals, which differs for this trait. Comparisons between the selected lines showed that adrenal function was stable in HGPS hens but not in LGPS hens in response to chronic social stress. Social stress-induced adrenal hypertrophy and its positive correlation with plasma corticosterone concentrations were found in the LGPS hens but not in the HGPS hens. The data demonstrated that chickens selected for variations in productivity and survivability variously altered the adrenal system in response to social stressors. The results suggest that these chicken lines could be valuable animal models for biomedical investigation of the effect of genetic-environmental interactions on the neuroendocrine function in controlling stress responses.