Peer-reviewed veterinary case report
Cisplatin chemotherapy for thyroid cancer in 13 dogs
By Fineman, L S et al.·Published in Journal of the American Animal Hospital Association·1998·Department of Veterinary Clinical Sciences, United States·View original on PubMed →
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Original publication title: Cisplatin chemotherapy for treatment of thyroid carcinoma in dogs: 13 cases.
- Species:
- dog
Plain-English summary
Thirteen dogs with thyroid cancer were treated with cisplatin chemotherapy, and most were around 10 years old. Among them, three were beagles, and many had large tumors attached to surrounding tissues. After treatment, one dog went into complete remission, while six showed partial improvement, and three had stable disease. Unfortunately, three dogs experienced worsening conditions. On average, the dogs lived about 192 days after starting chemotherapy, with some living longer than others.
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Abstract
The medical records of 13 dogs (10 spayed females, one intact male, one castrated male, and one dog of unknown gender) with histopathologically diagnosed thyroid carcinoma that were treated with cisplatin chemotherapy were reviewed. The mean age was 10.6 years. Three of the dogs were beagles. One dog had a c-cell medullary carcinoma, while the remaining 12 had follicular thyroid carcinoma. Eight of 13 dogs had tumors greater than 5 cm in diameter. In all 11 tumors for which information was available in the medical record, the masses were attached to underlying tissue. One dog underwent a complete remission, six had partial remissions, three had stable disease, and three had progressive disease. The mean time between initiation of cisplatin chemotherapy and development of progressive disease was 223.7 days (median, 202 days), with a mean survival time of 191.8 days (median, 98 days).
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/9507422/