Peer-reviewed veterinary case report
Clinical and anti-inflammatory effects of treating endotoxin-challenged pigs with meloxicam.
- Journal:
- The Veterinary record
- Year:
- 2006
- Authors:
- Friton, G M et al.
- Affiliation:
- Boehringer Ingelheim Animal Health · Germany
Abstract
The clinical and anti-inflammatory effects of a single treatment of 0.4 mg meloxicam/kg bodyweight on pigs that had been challenged with Escherichia coli endotoxin were investigated. Significantly lower total clinical scores were recorded in pigs treated with meloxicam than in pigs treated with a placebo. Significantly higher mean serum concentrations of thromboxane B(2) were also recorded in pigs treated with a placebo for up to 24 hours after the challenge. The serum concentrations of acute phase proteins and specific antibody titres to E coli lipopolysaccharide were unaffected by the meloxicam. The meloxicam treatment was well tolerated.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/17056651/