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Peer-reviewed veterinary case report

Horses with thickened bones and lameness - what to know about

By Ronen, N et al.·Published in Journal of the South African Veterinary Association·1992·Department of Medicine·View original on PubMed

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Original publication title: Clinical and biochemistry findings, and parathyroid hormone concentrations in three horses with secondary hyperparathyroidism.

Species:
horse

Plain-English summary

This report discusses three horses diagnosed with nutritional secondary hyperparathyroidism, a condition caused by an imbalance in their diet that affects calcium and phosphorus levels. The horses had noticeable thickening of their jaw bones, which may or may not have caused them to limp. Blood tests showed high levels of parathyroid hormone, an enzyme called alkaline phosphatase, and changes in how their bodies were handling phosphorus. The treatment details and outcomes are not specified, so it's unclear how well the horses responded to any interventions.

Abstract

Three cases of horses with nutritional secondary hyperparathyroidism (NSH) are described. The horses showed typical thickening of the maxillae and mandibular bones with or without lameness. Laboratory findings included elevated concentrations of parathyroid hormone (carboxy-terminal and mid-molecule fractions), alkaline phosphatase and an increase in the fractional excretion rate of serum inorganic phosphorus.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/1404225/