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Peer-reviewed veterinary case report

Clinical and clinicopathologic findings in two foals infected with Bacillus piliformis.

Journal:
Journal of the American Veterinary Medical Association
Year:
1988
Authors:
Humber, K A et al.
Affiliation:
Department of Clinical Studies · United States
Species:
horse

Plain-English summary

Two young horses, known as foals, were diagnosed with an infection caused by Bacillus piliformis, which is also called Tyzzer's disease. This type of infection is not often seen because it can progress very quickly. Both foals showed similar health issues, including low white blood cell counts, high levels of a protein called fibrinogen, imbalances in their body chemistry, and low blood sugar. Unfortunately, the treatments attempted did not help either foal, and they did not recover.

Abstract

Bacillus piliformis infection (Tyzzer's disease) in foals is rarely observed clinically because of the peracute course of the disease. Clinical and clinicopathologic findings as well as information on therapeutic attempts in two foals are described. Clinicopathologic abnormalities common to both cases included leukopenia, hyperfibrinogenemia, metabolic acidosis, and hypoglycemia. Treatment was unsuccessful in both cases.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/3209457/