Peer-reviewed veterinary case report
Progressive retinal atrophy signs and eye tests in South Korean
By Jeong, Man Bok et al.·Published in The Journal of veterinary medical science·2013·Department of Veterinary Clinical Sciences, South Korea·View original on PubMed →
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Original publication title: Clinical and electroretinographic findings of progressive retinal atrophy in miniature schnauzer dogs of South Korea.
- Species:
- dog
Plain-English summary
A group of miniature schnauzers in South Korea, aged 2 to 7 years, were found to have progressive retinal atrophy (PRA), a condition that affects their vision. Most of these dogs showed signs like poor response to visual cues and abnormal pupil reactions, indicating serious eye problems. Eye exams revealed changes in the retina, and tests showed that their eyes were not responding normally to light. Unfortunately, there is no cure for PRA, and affected dogs often experience worsening vision as they age.
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Abstract
The purpose of the study was to describe the clinical and electroretinographic features of clinical cases of progressive retinal atrophy (PRA) in miniature schnauzer (MS) of South Korea. Sixty-six MS (14 normal and 52 affected) were included. All animals underwent routine ocular examinations. Electroretinogram (ERG) was recorded in the 14 normal and 15 affected dogs. For normal dogs, the mean age ± SD was 4.1 ± 2.4 years (1 to 9 years), and there were no ocular abnormalities on the basis of ocular examinations and ERG results. For the PRA-affected dogs, it was shown that the mean age ± SD was 4.3 ± 1.1 years (2 to 7 years), and 44 dogs (84.6%) were 3 to 5 years old. Most of the PRA-affected dogs had abnormal menace responses (98.1%) and pupillary light reflexes (PLRs, 88.5%); some dogs showed normal menace response (1.9%) and PLRs (11.5%). Ophthalmoscopic abnormalities in the affected group included one or more of the following changes: hyperreflectivity and discoloration of the tapetal area, attenuation of retinal vessels, depigmentation in non-tapetal area and optic disc atrophy. ERG in the affected dogs showed non-recordable responses in all cases tested with clinical signs of PRA. The present study showed that PRA in MS was mainly observed between the age of 3 to 5 years. ERG revealed abnormal rod and cone responses in affected dogs at the ages studied.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/23719750/