Peer-reviewed veterinary case report
Effects of tiletamine and zolazepam anesthesia on blood and health
By Spada, Eva et al.·Published in Journal of Feline Medicine and Surgery·2014·Veterinary Transfusion Unit (REV), Department of Health, Animal Science and Food Safety (VESPA), University of Milan, Milan, Italy, Italy·View original on Crossref →
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Original publication title: Clinical and haematological responses of feline blood donors anaesthetised with a tiletamine and zolazepam combination
- Species:
- cat
Plain-English summary
A group of 31 healthy cats were given a combination of tiletamine and zolazepam to safely collect blood for donation. After the procedure, the cats showed a slight drop in body temperature but no serious side effects like weakness or pale gums. Their blood pressure increased, and while some blood cell counts changed, these were not significant enough to cause concern. Overall, the cats tolerated the blood donation well and recovered without issues.
People also search for: cat blood donation safety · feline anesthesia effects · tiletamine zolazepam for cats
Abstract
This prospective study investigated the effect on clinical and haematological variables of the anaesthetic combination of tiletamine and zolazepam in feline blood donors. Blood (10 ml/kg bodyweight to a maximum volume of 60 ml) was collected from the jugular vein of 31 owned healthy cats anaesthetised with 2.5 mg/kg of tiletamine and 2.5 mg/kg of zolazepam intramuscularly. Rectal temperature (RT), systolic arterial pressure (SAP), mean arterial pressure (MAP), diastolic arterial pressure (DAP), heart rate (HR) and complete blood count (including red blood cells [RBC], haemoglobin [HB], haematocrit [HT], platelet [PLT] count, white blood cells [WBC], lymphocytes, neutrophils, eosinophils, monocytes and basophils) were evaluated pre- and postdonation. RT decreased significantly ( P <0.01) after blood donation (mean change in RT −0.7°C). Significant increases in SAP ( P = 0.03), MAP ( P <0.01) and DAP ( P <0.01) occurred after blood donation (mean increase 13 mmHg, 12 mmHg and 11 mmHg, respectively). Although RBC, HT, HB, WBC, PLT, neutrophil and monocyte counts decreased, and HR, and lymphocyte, eosinophil and basophil counts increased after blood donation this change was not statistically significant. Mean time from pre- to postdonation evaluation was 39 ± 11 mins (range 24–76 mins). None of the cats had evidence of pallor or collapse after recovery from anaesthesia. The collection of blood at 10 ml/kg bodyweight to a maximum volume of 60 ml in healthy cats using a low dose tiletamine and zolazepam anaesthetic appears to be well tolerated by feline blood donors.
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Search related cases →Original publication on Crossref: https://doi.org/10.1177/1098612x14542452