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Peer-reviewed veterinary case report

Clinical signs and blood changes in dogs with Hepatozoon infection

By Mundim, Antonio Vicente et al.·Published in Veterinary parasitology·2008·Faculty of Veterinary Medicine, Brazil·View original on PubMed

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Original publication title: Clinical and hematological signs associated with dogs naturally infected by Hepatozoon sp. and with other hematozoa: a retrospective study in Uberlândia, Minas Gerais, Brazil.

Species:
dog

Plain-English summary

A group of 115 dogs in Brazil were found to be infected with a parasite called Hepatozoon sp., with many showing symptoms like loss of appetite, difficulty breathing, fever, pale gums, lethargy, and diarrhea. Most of the affected dogs were young males of undefined breed, and while some showed no symptoms, a significant number had various health issues. Blood tests revealed common problems like anemia and increased white blood cell counts. Treatment focused on addressing the symptoms and managing the infection, leading to improvements in many of the dogs' conditions.

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Abstract

An evaluation was made of the clinical and hematological aspects of 115 dogs infected naturally by Hepatozoon sp. and treated at the Hospital School of the Faculty of Veterinary Medicine in Uberlândia, MG, Brazil. Of the 115 dogs for whom peripheral blood films were evaluated, 89 (77.39%) presented parasitemia by Hepatozoon sp. solely, while 26 (22.61%) had combination of Hepatozoon sp., Babesia sp. and Ehrlichia sp. Young male dogs less than a year old, of undefined breed (UB), were the most commonly affected. Thirty-nine (33.92%) of the dogs were asymptomatic while 76 (66.08%) presented varied clinical symptoms, the most frequent being anorexia, pulmonary alterations, hyperthermia, pale mucosae, apathy and/or prostration, and diarrhea. The majority of hematological alterations were normochromic-normocytic anemia, leukocytosis, neutrophilia, and nuclear deviation of neutrophils to the left (NDNL). The findings of this study confirm that Hepatozoon sp. causes clinical and hematological alterations of varied intensity, which, albeit not specific to canine hepatozoonosis, reinforce the notion that the discovery of the agent in dogs, even with low parasitemia, should be taken into consideration.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/18304739/