Peer-reviewed veterinary case report
Cat vomiting and anemia caused by splenic mast cell tumor
By S Lee et al.·Published in Veterinární Medicína·2021·Department of Veterinary Internal Medicine and Institute of Veterinary Science, College of Veterinary Medicine, Kangwon National University, Chuncheon, Republic of Korea, CZ·View original on DOAJ →
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Original publication title: Clinical and immunohistochemical findings of splenic mast cell tumour in a cat: A case report
- Species:
- cat
Plain-English summary
A 6-year-old female domestic shorthair cat was brought in for chronic vomiting and not eating for four months. Tests showed she had anemia and an enlarged spleen filled with abnormal mast cells, leading to a diagnosis of a splenic mast cell tumor. The vet performed surgery to remove the spleen and treated her with chemotherapy, which included vinblastine and prednisolone. After treatment, her anemia improved, and her vomiting and appetite returned to normal.
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Abstract
A 6-year-old, spayed, female, domestic shorthair cat presented with a 4-month history of chronic intermittent vomiting and anorexia. The haematologic results indicated moderate anaemia and a circulating mast cell population. The abdominal radiography revealed a markedly enlarged spleen. The cytological analysis of the spleen showed a uniform population of mast cells, and a diagnosis of systemic mastocytosis (splenic mast cell tumour with mastocytaemia) was made. This diagnosis was subsequently confirmed by the histopathological examination of the spleen. The immunohistochemistry for KIT showed KIT pattern II (focal cytoplasmic expression). A splenectomy and chemotherapy with vinblastine and prednisolone resulted in remission of the anaemia and other clinical signs. This case report highlights the importance of cytological evaluations of peripheral blood smears and/or aspirates of enlarged spleens for diagnosing splenic mast cell tumours and for quickly initiating the appropriate treatment.
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Search related cases →Original publication on DOAJ: https://doi.org/10.17221/11/2021-VETMED