Peer-reviewed veterinary case report
Mixed-breed dog with seizures and smooth brain diagnosed by MRI
By Lee, Kyo-Im et al.·Published in The Journal of veterinary medical science·2011·BK21 Basic & Diagnostic Veterinary Specialist Program for Animal Diseases and Department of Veterinary Internal Medicine, South Korea·View original on PubMed →
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Original publication title: Clinical and MRI findings of lissencephaly in a mixed breed dog.
- Species:
- dog
Plain-English summary
A 7-year-old male mixed-breed dog was brought in for sudden pain and had been experiencing seizures for two years. An MRI of his brain showed a smooth surface instead of the usual folds, indicating a condition called lissencephaly, along with other issues in the spine. The dog also had problems with his spinal discs that were pressing on his spinal cord. After treatment for his seizures and neck pain, the dog's symptoms completely resolved, and he was feeling much better.
People also search for: dog seizures treatment · mixed-breed dog neck pain · lissencephaly in dogs
Abstract
A 7-year-old castrated male mixed-breed dog was presented with a complaint of acute pain. The dog had suffered from isolated seizures for two years. Magnetic resonance imaging (MRI) of the brain revealed a smooth brain surface due to lack of gyri and sulci formation of the cerebrum and thick cortical grey matter. Additionally, ventriculomegaly and an arachnoid cyst were noted. Multiple spinal cord compressions induced by intervertebral disc protrusion were observed on a cervical MRI. Based on these findings, the dog was diagnosed as having lissencephaly concurrent with intervertebral cervical disease. After therapy for seizure and cervical pain, the clinical signs were completely resolved. To the author's knowledge, this is the case report to diagnose lissencephaly in a mixed-breed dog.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/21685716/