Peer-reviewed veterinary case report
Dog with severe skin thickening and folds
By Guaguère, E et al.·Published in The Journal of small animal practice·2024·Dermatology Referral Service, France·View original on PubMed →
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Original publication title: Clinical and pathological characteristics of a dog with scleromyxoedema.
- Species:
- dog
Plain-English summary
An 8-year-old male cross-Labrador retriever was brought in because he was developing thick folds of skin all over his body. The vet diagnosed him with scleromyxoedema, a rare skin condition, after noticing severe skin thickening and other symptoms. Despite treatment with prednisolone to help reduce the skin issues, the dog continued to struggle with mobility due to severe arthritis and ultimately had to be euthanized six months later because he could no longer walk.
People also search for: dog skin folds treatment · scleromyxoedema in dogs · Labrador retriever skin problems · dog arthritis management · why is my dog having skin issues
Abstract
An 8-year-old male cross-Labrador retriever was presented for a progressive appearance of folds all over the body of the dog. Scleromyxoedema was diagnosed based on clinical signs and histopathological features. Clinical signs were characterised by a papular and vesicular eruption and severe skin thickening causing exuberant folds along with concurrent severe osteoarthritis of the coxofemoral joints. Thyroid disorders were excluded and the condition was not associated with monoclonal gammopathy. Histopathological features consisted of mucin deposition, fibroblast proliferation and fibrosis. Prednisolone was prescribed to decrease mucin synthesis which allowed a marked clinical improvement. Due to the progressive inability to walk, the dog was euthanased 6 months after the first consultation.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/39308349/