Peer-reviewed veterinary case report
Clinical application of cerebrospinal fluid creatine phosphokinase determination.
- Journal:
- Journal of the American Veterinary Medical Association
- Year:
- 1977
- Authors:
- Wilson, J W
- Species:
- cat
Plain-English summary
In a study involving 126 animals suspected of having central nervous system diseases, researchers measured a substance called creatine phosphokinase in their cerebrospinal fluid, which is the fluid surrounding the brain and spinal cord. They found that 32 samples had low levels of this substance, while 94 samples had levels that were still considered low. However, they noticed that levels were high in all cases of two specific diseases in cats: toxoplasmosis and feline infectious peritonitis. The findings also suggested that measuring this substance could help in understanding other conditions, like seizure disorders and potential poisonings. Overall, the study indicates that this test can be useful in diagnosing certain diseases in pets.
Abstract
Creatine phosphokinase activity was determined in cerebrospinal fluid samples submitted for analysis from 126 animals suspected of having central nervous system disease. Values less than 1 sigma unit/ml were obtained on 32 samples and values less than or equal to 1 sigma unit/ml were obtained on 94 samples. The creatine phosphokinase values were increased in all cases of feline toxoplasmosis and feline infectious peritonitis. From other cases, especially seizure disorders and suspected poisonings, and apparent aid in prognosis for future cases was identified.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/885773/