Peer-reviewed veterinary case report
Clinical behavior of intraocular teratoid medulloepithelioma in two-related Quarter Horses.
- Journal:
- Veterinary ophthalmology
- Year:
- 2017
- Authors:
- Monk, Caroline S et al.
- Affiliation:
- Department of Small Animal Clinical Sciences · United States
- Species:
- horse
Plain-English summary
This study looked at two related Quarter Horses that both had a rare eye tumor called intraocular teratoid medulloepithelioma. The first horse was a 3-year-old gelding who had a cyst-like mass in his eye and was treated by removing the eye. Unfortunately, 15 months later, he developed swelling and other signs that indicated the tumor had spread, and he passed away. The second horse, a 9-year-old mare, had a similar tumor but was treated successfully with eye removal, and she has not had any problems for two years since the surgery. The findings suggest that this type of tumor can spread, so it's important to monitor related horses closely.
Abstract
The objective of this paper is to describe clinical behavior, histopathologic features, and immunohistochemical staining of two-related horses with intraocular teratoid medulloepithelioma. Two-related Quarter Horses with similar intraocular masses presented to the UF-CVM Comparative Ophthalmology Service for evaluation and treatment. The first horse, a 3-year-old gelding, had glaucoma and a cyst-like mass in the anterior chamber. Enucleation was performed. Histopathology revealed a teratoid medulloepithelioma. The tumor was considered to be completely excised. Fifteen months later, the gelding presented with swelling of the enucleated orbit and local lymph nodes with deformation of the skull. Cytology revealed neuroectodermal neoplastic cells. Necropsy confirmed tumor metastasis. Six weeks later, a 9-year-old mare, a full sibling to the gelding, presented for examination. An infiltrative mass of the iris and ciliary body was found that extended into the anterior, posterior, and vitreal chambers. Uveitis was present, but secondary glaucoma was not noted. Enucleation was performed and the histopathologic diagnosis was also teratoid medulloepithelioma. The mare has had no recurrence to date, 2 years following enucleation. Metastasis of intraocular teratoid medulloepithelioma is possible. Staging is recommended in cases where the diagnosis of teratoid medulloepithelioma is confirmed. Surveillance of full siblings is recommended until more information regarding etiology is known.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/27440405/