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Peer-reviewed veterinary case report

Dog with optic nerve tumor spreading into brain and eye area

By Charnock, Lauren N et al.·Published in The Canadian veterinary journal = La revue veterinaire canadienne·2023·Department of Clinical Sciences, United States·View original on PubMed

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Original publication title: Clinical description with magnetic resonance appearance of a high-grade undefined optic nerve glioma with intracranial extension.

Species:
dog

Plain-English summary

A 4-year-old mixed-breed dog was brought in for bleeding in the eye (hyphema) and increased pressure in the eye (glaucoma). The veterinarian performed surgery to remove the affected eye, but later tests showed a tumor on the optic nerve that had spread into the brain. Unfortunately, the dog's condition worsened over the next few months, leading to a decline in mental alertness and vision in the other eye. The dog was euthanized about four and a half months after the initial visit, and the tumor was confirmed during a post-mortem examination.

People also search for: dog eye bleeding treatment · glaucoma in dogs · optic nerve tumor in dogs

Abstract

A 4-year-old mixed-breed dog was presented for hyphema and glaucoma of the right eye. Enucleation of the right globe was carried out, and histopathology examination revealed an optic nerve glioma with incomplete surgical margins. At 8 wk after surgery, the dog had depressed mentation and a diminished pupillary light reflex of the left eye. Magnetic resonance imaging revealed an irregular, heterogeneously T2 hyperintense/T1 isointense mass in the region of the optic chiasm. Compression of the rostral thalamus was present, with effacement of the pituitary gland and involvement of the right orbit. The dog was euthanized 4.5 mo after initial presentation. An undefined glioma of the right optic nerve with extension to the diencephalon was diagnosed on necropsy. Key clinical message: Although rare, intraocular glioma is a differential diagnosis for hyphema, glaucoma, and retinal detachment. Magnetic resonance imaging should be considered in cases of intraocular neoplasia, notably in those with incomplete surgical margins of the optic nerve.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/37529389/