Peer-reviewed veterinary case report
Radionuclide injection for early elbow arthritis in 44 dogs
By Lattimer, Jimmy et al.·Published in Veterinary radiology & ultrasound : the official journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association·2023·Department of Veterinary Medicine and Surgery, United States·View original on PubMed →
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Original publication title: Clinical effectiveness and safety of intraarticular administration of aTin radiocolloid (Synovetin OA) for treatment of early and intermediate grade osteoarthritis of the elbow in a dose finding study conducted in 44 dogs.
- Species:
- dog
Plain-English summary
A group of 44 dogs with elbow osteoarthritis, often caused by elbow dysplasia, received a special injection to help reduce pain and inflammation in their affected joints. The dogs were given different doses of a radiocolloid treatment and were monitored over a year. Both the owners and veterinarians noticed improvements in pain levels, with the medium dose showing the best and longest-lasting results. This treatment could be a promising option for dogs suffering from this type of arthritis.
People also search for: dog elbow arthritis treatment · osteoarthritis pain relief for dogs · elbow dysplasia in dogs · radiocolloid injection for dogs
Abstract
Osteoarthritis of the elbow joint secondary to elbow dysplasia is common in dogs. Intraarticular radionuclide injection is thought to suppress both synovitis and inflammatory pain mediators in the joint which are not directly addressed by current treatments. This dose-finding investigation was a longitudinal, prospective, experimental parallel group, post-test study with repeated measures. Forty-four dogs, with low to intermediate-grade osteoarthritis, received a single injection into their most clinically affected elbow joint and were randomized into three treatment cohorts; 37 MBq, 64.75 MBq, or 92.5 MBq (normalized to the body surface area of a 22 kg dog) ofSn radiocolloid. Dogs were assessed monthly by owners, using the canine Brief Pain Inventory (cBPI), and at 1, 3, 6, 9, and 12 months intervals by investigators. Positive responses to treatment were observed by both owners and clinicians in all dose groups with the medium dose group having the highest and most durable response rate based on cBPI scores. The results of this study support the use ofSn radiocolloid as a primary treatment of osteoarthritis in low to intermediate-grade osteoarthritis of the canine elbow.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/36507585/