Peer-reviewed veterinary case report
Bleomycin treatment clears warts in two 8-month-old Pug puppies
By Erdoğan, Songül et al.·Published in Bozok Veterinary Sciences·2024·Aydın Adnan Menderes Üniversitesi, Veteriner Fakültesi, İç Hastalıkları Anabilim Dalı, Aydın, Türkiye·View original on Crossref →
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Original publication title: Clinical Efficacy of Bleomycin in Canine Papillomatosis: Case Report of Two Sibling Puppies
- Species:
- dog
Plain-English summary
Two 8-month-old male Pug puppies were brought to the vet because they had multiple warts on their lips and chin, which were diagnosed as canine papillomatosis (CP). The vet treated them with a medication called bleomycin, given as an injection once a week. After 6 weeks, one puppy's warts completely disappeared, while the other puppy's warts were gone by 9 weeks. Both puppies showed no side effects during treatment, and the warts did not return.
People also search for: puppy warts treatment · canine papillomatosis in Pugs · bleomycin for dog warts
Abstract
Aim: The objective was to assess the clinical efficacy of anti-tumoral bleomycin on canine papillomatosis (CP) in two male Pug breed sibling puppies. Material and Methods: Two 8 month-old, male sibling puppies were presented with multiple warts in the lip and chin. A suspected diagnosis of CP was established through only clinical examination with appearance of typical cauliflower-like warts. Bleomycin was subcutaneously administered to both siblings on a weekly by 0.5 IU/kg dosage. Results: At week 6, one of the siblings exhibited complete regression of oral lesions, whereas the other sibling achieved complete healing by week 9. The warts persistently show complete resolution, with no new lesions. No adverse effects were observed, verified through weekly blood count and physical examination during and post-treatment. Conclusion: Subcutaneous administration of bleomycin at weekly at a dose of 0.5 IU/kg contributed to the regression of oral lesions and improved clinical outcomes in dogs, suggesting potential efficiency in the treatment of CP.
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Search related cases →Original publication on Crossref: https://doi.org/10.58833/bozokvetsci.1425583