Peer-reviewed veterinary case report
Kitten with fluid from feline infectious peritonitis
By Kameshima, Satoshi et al.·Published in The Journal of veterinary medical science·2020·School of Veterinary Medicine, Japan·View original on PubMed →
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Original publication title: Clinical efficacy of combination therapy of itraconazole and prednisolone for treating effusive feline infectious peritonitis.
- Species:
- cat
Plain-English summary
A 3-month-old male Scottish Fold kitten was brought to the vet with fluid in his chest and abnormal blood protein levels. Tests showed he had effusive feline infectious peritonitis (FIP), caused by a type of coronavirus. The kitten was treated with itraconazole, an antifungal, and prednisolone, a steroid, which helped improve his blood protein levels and reduced the chest fluid. Unfortunately, after 38 days, he developed severe neurological issues and had to be euthanized due to status epilepticus (a type of seizure). While itraconazole showed some positive effects, more research is needed on its use for FIP.
People also search for: kitten FIP treatment · Scottish Fold kitten seizures · itraconazole for cats · prednisolone for cat infections
Abstract
A 3-month-old male Scottish Fold kitten with pleural fluid and low ratio of albumin to globulin (A/G ratio) was brought to our small animal hospital. Since RNA from the type I feline coronavirus (FCoV) were detected in drained pleural fluid, the cat was tentatively diagnosed with effusive feline infectious peritonitis (FIP). Following the administration of itraconazole and prednisolone, the A/G ratio increased, and the pleural fluid mostly disappeared. The fecal FCoV levels temporarily decreased. However, the cat showed neurological manifestations and was eventually euthanized due to status epilepticus after 38 days of treatment. In conclusion, itraconazole partly exerted a beneficial effect in a cat with FIP. However, further investigation of a possible role of itraconazole in FIP treatment is warranted.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/32848107/