Peer-reviewed veterinary case report
Pimobendan vs benazepril for heart valve disease in dogs
By Lombard, Christophe W et al.·Published in Journal of the American Animal Hospital Association·2006·Klinik fü·View original on PubMed →
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Original publication title: Clinical efficacy of pimobendan versus benazepril for the treatment of acquired atrioventricular valvular disease in dogs.
- Species:
- dog
Plain-English summary
A group of 76 dogs with heart disease were treated with either pimobendan or benazepril to see which medication worked better. The dogs receiving pimobendan showed significant improvement in their heart function within 56 days and had a longer survival time compared to those on benazepril. Specifically, dogs on pimobendan lived a median of 415 days, while those on benazepril lived about 128 days. This suggests that pimobendan may be a more effective treatment option for dogs with this type of heart condition.
People also search for: dog heart disease treatment · pimobendan vs benazepril for dogs · dog heart medication effectiveness
Abstract
Seventy-six dogs with clinical acquired atrioventricular valvular disease were evaluated to determine the efficacy of pimobendan (n=41) versus benazepril hydrochloride (n=35) in a randomized, positive-controlled, multicenter study. The study was divided into 56-day and long-term evaluation periods. In a subgroup of dogs with concurrent furosemide treatment (pimobendan [n=31], benazepril [n=25]), the Heart Insufficiency Score improved in favor of pimobendan (P=0.0011), equating to a superior overall efficacy rating (P<0.0001) at day 56. Long-term median survival (i.e., death or treatment failure) for dogs receiving pimobendan was 415 days versus 128 days for dogs not on pimobendan (P=0.0022).
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/16822763/