Peer-reviewed veterinary case report
Budesonide does not improve inflammatory bowel disease symptoms
By Rychlik, A et al.·Published in Polish journal of veterinary sciences·2016·View original on PubMed →
PetCaseFinder translated the abstract of this peer-reviewed paper into plain English so pet owners can read it. We do not publish original research — every detail traces back to the citation above. How we work →
Original publication title: Clinical, endoscopic and histopathological evaluation of the efficacy of budesonide in the treatment of inflammatory bowel disease in dogs.
- Species:
- dog
Plain-English summary
A group of dogs with inflammatory bowel disease (IBD) were treated with budesonide, a medication aimed at reducing their symptoms. Unfortunately, the treatment did not help improve their clinical signs, such as diarrhea or vomiting, nor did it make their intestinal lining look better during examinations. While there were some changes seen under a microscope in the tissue samples, overall, budesonide was not effective for managing IBD in these dogs. Pet owners should discuss alternative treatments with their veterinarian if their dog has IBD.
People also search for: dog inflammatory bowel disease treatment · budesonide for dogs · dog diarrhea medication options
Abstract
This study evaluates the efficacy of budesonide in the treatment of inflammatory bowel disease (IBD) in dogs based on the results of clinical, endoscopic and histopathological examinations. The severity of clinical symptoms was assessed based on CIBDAI scores, and macroscopic and histopathological changes were described in accordance with the recommendations of the WSAVA Gastrointestinal Standardization Group for 2008. The results of the experiment revealed that budesonide does not offer effective treatment for canine IBD. The tested drug failed to alleviate the clinical symptoms of disease, lower CIBDAI scores, or improve the macroscopic appearance of intestinal mucosa. The effectiveness of budesonide was most highly evaluated in the histopathological picture of duodenal, jejunal and colonic mucosa.
Find similar cases for your pet
PetCaseFinder finds other peer-reviewed reports of pets with the same symptoms, plus a plain-English summary of what was tried across them.
Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/27096800/