Peer-reviewed veterinary case report
Diet with Siraitia grosvenorii extract helps dogs with atopic
By Park, Mi-Kyung et al.·Published in BMC veterinary research·2025·Research Institute of Veterinary Medicine, South Korea·View original on PubMed →
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Original publication title: Clinical evaluation of a functional diet containing Siraitia grosvenorii residual extract for atopic dermatitis in dogs: a self-controlled study.
- Species:
- dog
Plain-English summary
A group of 32 dogs with atopic dermatitis (a chronic skin condition causing itching and inflammation) were studied to see if a special diet containing Siraitia grosvenorii extract could help. For 12 weeks, the dogs were fed a standard diet, followed by 12 weeks on the functional diet. During the treatment phase, the dogs showed significant improvements in their skin condition and itching, with many owners reporting satisfaction with the results. The diet was well tolerated, suggesting it could be a helpful addition to managing atopic dermatitis in dogs.
People also search for: dog atopic dermatitis treatment · Siraitia grosvenorii for dogs · dog itching relief diet
Abstract
BACKGROUND: Canine atopic dermatitis (CAD) is a chronic inflammatory skin disease that significantly impairs quality of life. Nutritional interventions have gained attention as supportive therapeutic strategies. This study investigated the clinical efficacy and safety of a functional diet containing Siraitia grosvenorii residual extract by evaluating its effects on clinical symptoms and inflammatory markers in dogs with CAD using a self-controlled design. METHODS: A total of 32 dogs diagnosed with CAD were fed a standard diet for 12 weeks (control phase) followed by a functional diet for 12 weeks (treatment phase). Clinical assessments, including transepidermal water loss (TEWL), Canine Atopic Dermatitis Extent and Severity Index (CADESI-04), Pruritus Visual Analog Scale (PVAS), Owner Global Assessment of Treatment Efficacy (OGATE), and serum IgE levels were conducted at baseline and at 6-week intervals. RESULTS: TEWL, CADESI-04, and PVAS scores significantly improved during the treatment phase compared with the control phase (p = 0.0002, < 0.0001, and < 0.0001, respectively). No significant difference was observed in serum in serum IgE levels (p = 0.8046). The OGATE responses indicated 80.65% rate of owner-reported satisfaction. CONCLUSIONS: The functional diet significantly improved the clinical signs of CAD and was well tolerated. These findings suggest that nutritional support with the Siraitia grosvenorii extract may be a beneficial adjunctive therapy for CAD.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/41194120/