Peer-reviewed veterinary case report
Signs and survival of Addison's disease in soft-coated wheaten
By Haviland, Rebecca L et al.Ā·Published in The Canadian veterinary journal = La revue veterinaire canadienneĀ·2016Ā·Department of Clinical Studies-Philadelphia, United StatesĀ·View original on PubMed ā
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Original publication title: Clinical features of hypoadrenocorticism in soft-coated wheaten terrier dogs: 82 cases (1979-2013).
- Species:
- dog
Plain-English summary
A 3.5-year-old soft-coated wheaten terrier was diagnosed with hypoadrenocorticism, a condition where the adrenal glands don't produce enough hormones. Symptoms included abnormal blood levels, such as low sodium and high potassium, which are common in this breed. Some dogs also developed kidney issues, leading to a shorter survival time. On average, these dogs lived about 5.4 years after diagnosis, but those with normal sodium and potassium levels had a shorter lifespan. Treatment options typically focus on hormone replacement and managing any kidney problems.
People also search for: soft-coated wheaten terrier adrenal disease symptoms Ā· dog kidney problems treatment Ā· hypoadrenocorticism in dogs survival rate
Abstract
The objective of this retrospective case series, which included 82 client-owned soft-coated wheaten terriers, was to characterize clinical features of hypoadrenocorticism in this breed. Median age at diagnosis was 3.5 years. There was no gender predilection. Clinicopathologic findings included sodium/potassium ratio < 27 (85%), hyperkalemia (76%), hyponatremia (63%), elevated blood urea nitrogen (83%) or creatinine (71%), and hypercalcemia (36%). Nine dogs with normal sodium and potassium (11%) were older and less often azotemic, hyperphosphatemic, or hypercalcemic. Twenty-one dogs (26%) developed protein-losing nephropathy (n = 18) and/or end-stage renal disease (n = 3). Overall median survival time was 5.4 years, but was shorter in dogs with normal sodium and potassium at diagnosis (4.2 years), or those with subsequent protein-losing nephropathy (4.2 years). This population showed no gender predilection, unlike that reported in the general canine population with hypoadrenocorticism, and more comorbid protein-losing nephropathy than in the general soft-coated wheaten terrier population.
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Search related cases āOriginal publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/27041756/