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Peer-reviewed veterinary case report

Signs and survival in 32 dogs with urosepsis 2017-2018

By Perry, Kayla M et al.·Published in Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001)·2022·Department of Clinical Sciences, United States·View original on PubMed

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Original publication title: Clinical features, outcome, and illness severity scoring in 32 dogs with urosepsis (2017-2018).

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Plain-English summary

A group of 32 dogs diagnosed with urosepsis, a serious infection often linked to conditions like pyometra (uterine infection), prostatitis (prostate infection), or pyelonephritis (kidney infection), were treated at a veterinary hospital. Most of the dogs, about 87.5%, survived their illness, with all dogs suffering from pyometra recovering fully. The most common bacteria found in these infections were E. coli and Klebsiella pneumoniae. The study highlighted that dogs with more severe illness had a higher number of dysfunctional organs, which could help vets assess and manage similar cases in the future.

People also search for: dog urosepsis treatment · symptoms of pyometra in dogs · dog kidney infection recovery

Abstract

OBJECTIVE: To describe the clinical features, outcome, and utility of illness severity scoring in dogs diagnosed with urosepsis. DESIGN: Retrospective study (2017-2018). SETTING: University teaching hospital. ANIMALS: Thirty-two dogs diagnosed with urosepsis secondary to pyometra, prostatitis, or pyelonephritis. INTERVENTIONS:  None. MEASUREMENTS AND MAIN RESULTS: Urosepsis was identified in 32 dogs, consisting of 9 of 32 (28.1%) with pyometra, 7 of 32 (21.8%) with prostatitis, and 16 of 32 (50%) with pyelonephritis. In total, 28 (87.5%) dogs survived to discharge, with the following group-specific survival rates: pyometra, 9 of 9 (100%); prostatitis, 5 of 7 (71.4%); and pyelonephritis, 14 of 16 (87.5%). Positive bacterial cultures were obtained in 27 of 32 (84.1%) dogs. The most commonly implicated pathogens were Escherichia coli (14/37 [37.8%]), Klebsiella pneumoniae (8/37 [21.6%]), and Staphylococcus pseudintermedius (6/37 [16.2%]). Multiple organ dysfunction syndrome (MODS) was identified in 21 of 32 dogs (65.6%). Although the presence of MODS was not different between survivors and nonsurvivors (P = 0.6), nonsurvivors had more dysfunctional organs (P = 0.04). Nonsurvivors also had higher Acute Patient Physiology and Laboratory Evaluation (APPLE) scores compared to survivors (P = 0.01). CONCLUSIONS: Survival of dogs with urosepsis was good and may be higher than for other sources of sepsis. Compared to survivors, nonsurvivors had more dysfunctional organs and higher illness severity scores, which may be helpful in the assessment and management of dogs with urosepsis.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/34730876/