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Peer-reviewed veterinary case report

Clinical, genetic, and pathological features of male pseudohermaphroditism in dog.

Journal:
Reproductive biology and endocrinology : RB&E
Year:
2011
Authors:
Bigliardi, Enrico et al.
Affiliation:
Faculty of Veterinary Medicine · Italy
Species:
dog

Abstract

Male pseudohermaphroditism is a sex differentiation disorder in which the gonads are testes and the genital ducts are incompletely masculinized. An 8 years old dog with normal male karyotype was referred for examination of external genitalia abnormalities. Adjacent to the vulva subcutaneous undescended testes were observed. The histology of the gonads revealed a Leydig and Sertoli cell neoplasia. The contemporaneous presence of testicular tissue, vulva, male karyotype were compatible with a male pseudohermaphrodite (MPH) condition.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/21255434/