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Peer-reviewed veterinary case report

Oral papillary squamous cell cancer in dogs and CT scan features

By Soukup, Jason W et al.·Published in Journal of veterinary dentistry·2013·Department of Surgical Sciences, United States·View original on PubMed

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Original publication title: Clinical, histologic, and computed tomographic features of oral papillary squamous cell carcinoma in dogs: 9 cases (2008- 2011).

Species:
dog

Plain-English summary

A group of large breed dogs, averaging about 4 years old, were diagnosed with oral papillary squamous cell carcinoma, a type of mouth cancer. Most of these dogs had tumors located in the upper jaw, and imaging showed that the cancer had invaded nearby bone but hadn’t spread to other parts of the body. All dogs underwent surgery to remove the tumors, and the procedure was successful with clean margins, meaning no cancer was left behind. On average, these dogs remained cancer-free for over a year after treatment.

People also search for: dog mouth cancer symptoms · oral squamous cell carcinoma treatment in dogs · large breed dog cancer survival rate

Abstract

Medical records of dogs diagnosed with oral papillary squamous cell carcinoma between December 2008 and April 2011 were reviewed. Information abstracted included signalment, tumor location, tumor size, computed tomographic (CT) features, evidence of metastatic disease based on cytologic examination of lymph node aspirates and thoracic radiography, treatment, surgical margins, histologic features, and treatment outcome. Dogs included in the study were all sexually altered, predominantly large breed dogs with a mean age of 3.9-years (range, 0.5 to 9.0-years). The most common location was the rostral maxilla. Invasion of underlying bone and lymphadenopathy were evident on CT imaging in most dogs. No evidence of metastasis was found on mandibular lymph node cytology and thoracic radiography. Histologic analysis revealed similar morphologic findings for all surgically resected tumors. Surgical excision with 1-2 cm margins was complete in all cases, with a mean tumor-free interval of 12.1-months.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/23757821/