Peer-reviewed veterinary case report
Skin redness and bumps in dogs after yeast exposure study
By Bond, R et al.·Published in Medical mycology·2004·Department of Veterinary Clinical Sciences, United Kingdom·View original on PubMed →
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Original publication title: Clinical, histopathological and immunological effects of exposure of canine skin to Malassezia pachydermatis.
- Species:
- dog
Plain-English summary
Ten Beagle dogs had a daily application of a yeast called Malassezia pachydermatis on their skin for a week to see how it affected them. Some dogs developed mild skin irritation, like redness and small bumps, especially when their skin was covered. The irritation was more severe where the yeast was applied compared to untreated areas. Fortunately, these skin issues resolved within about three weeks after stopping the treatment. This study suggests that healthy dog skin can resist infections from this yeast due to its immune responses.
People also search for: dog skin irritation yeast infection · Beagle skin problems · Malassezia treatment for dogs
Abstract
The effects of the daily application for 7 days of suspensions of Malassezia pachydermatis to normal canine skin were evaluated in 10 beagle dogs. Four out of six dogs challenged without occlusion developed transient lesions generally characterized clinically by mild erythema with papules and histologically by mild epidermal hyperplasia and a superficial perivascular dermatitis. Saline-treated control sites showed no clinical signs. In four dogs challenged with occlusion, skin lesions occurred at both yeast and saline-treated sites; erythema and papules were more severe at the yeast-treated sites in three dogs. Occlusion induced more persistent lesions, which resolved within 24 days. Population densities of the yeast were highest at day 8 and declined rapidly following cessation of application. Peripheral blood mononuclear cell proliferation indices following M. pachydermatis exposure in vitro and serum concentrations of M. pachydermatis-specific IgG antibodies did not vary significantly during the study. Delayed (24 h) intradermal test reactivity to M. pachydermatis antigens developed in all eight dogs with clinical signs following yeast exposure. This study suggests that the resistance of healthy canine skin to infection by M. pachydermatis is mediated by local delayed hypersensitivity responses and, or innate epidermal immune mechanisms.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/15124870/