Peer-reviewed veterinary case report
Skin nodules on dog ears and face from leproid granuloma in US dogs
By Foley, J E et al.·Published in Veterinary pathology·2002·Department of Medicine and Epidemiology, United States·View original on PubMed →
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Original publication title: Clinical, microscopic, and molecular aspects of canine leproid granuloma in the United States.
- Species:
- dog
Plain-English summary
A group of seven dogs in the United States developed leproid granulomas, which are nodular and ulcerated skin lesions mainly found on their ears, faces, and legs. Most of the dogs showed complete healing within six months, either without any treatment or after having the lesions surgically removed. Tests revealed inflammation and the presence of specific bacteria, but these bacteria could not be grown in a lab. Fortunately, the outlook for these dogs is very positive, especially compared to other more serious mycobacterial infections.
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Abstract
Leproid granulomas from seven dogs in the United States were evaluated. Gross characteristics included nodular and ulcerated dermal and subcutaneous lesions primarily on the caudal aspects of the pinnae and to a lesser extent on the muzzle, face, and forelimbs. In all except one dog, there was complete regression of the lesions within 6 months, either with no therapy or after surgical resection. Cytology or histopathology revealed pyogranulomatous inflammation with few to many acid-fast mycobacterial bacilli within macrophages. The organisms could not be cultivated in vitro. DNA sequencing of part of the 16S ribosomal RNA gene region revealed 99-100% homology among fragments from five of these dogs and fragments from dogs in the south Pacific. This syndrome occurs in dogs in North America and the prognosis is excellent, in contrast to the prognosis for rapid-growing or tuberculous mycobacteriosis.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/12009061/