Peer-reviewed veterinary case report
Outcomes of surgery for mast cell tumors on dog ears
By Schwab, Timothy M et al.·Published in Journal of the American Animal Hospital Association·2014·Department of Surgery, United States·View original on PubMed →
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Original publication title: Clinical outcome for MCTs of canine pinnae treated with surgical excision (2004-2008).
- Species:
- dog
Plain-English summary
A group of dogs with mast cell tumors (MCTs) on their ears underwent surgery to remove the tumors. The study found that dogs with lower-grade tumors (grade 1 and 2) had a good chance of not having the tumors come back, while those with higher-grade tumors (grade 3) faced a much poorer outcome, often experiencing recurrence and shorter survival times. Specifically, dogs with grade 3 tumors lived about 10 months after surgery, while those with lower grades had better prospects. This suggests that early detection and treatment of lower-grade MCTs can lead to a more favorable outcome.
People also search for: dog ear tumor treatment · mast cell tumor prognosis in dogs · grade 3 mast cell tumor survival time
Abstract
Canine mast cell tumors (MCTs) are the most common cutaneous neoplasm in the dog. It has been suggested that MCT in certain locations may behave in a more biologically aggressive fashion than MCTs located in others; however, no published data are available for MCTs of canine pinnae treated with surgical excision. A retrospective study of 28 animals with surgical excision of MCTs of pinnae was completed with a medical record review and follow-up questionnaire to the operating veterinarian. The effect of tumor grade, clean or dirty excision, cartilage penetration, and mitotic index (MI) on local recurrence and survival time (ST) was evaluated. There was local recurrence in one dog with a grade 2 MCT and in seven of eight dogs with grade 3 MCTs. The median ST of animals with grade 1 and 2 MCTs was not reached, whereas the median ST of animals with grade 3 MCTs was 10 mo. There was no statistical association between histologically clean and dirty margins and either local recurrence or ST. A prolonged disease free interval without local recurrence may be achieved with local excision of grade 1 and 2 MCTs. Animals with grade 3 MCTs had a uniformly poor outcome with short times to local recurrence and death.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/24659731/