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Peer-reviewed veterinary case report

Nasal tumor radiation treatment results in dogs and survival times

By Hunley, David W et al.·Published in The Canadian veterinary journal = La revue veterinaire canadienne·2010·Ocean State Veterinary Specialists, United States·View original on PubMed

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Original publication title: Clinical outcome in dogs with nasal tumors treated with intensity-modulated radiation therapy.

Species:
dog

Plain-English summary

Twelve dogs with nasal tumors were treated with a specialized type of radiation therapy called intensity-modulated radiation therapy (IMRT). During the treatment, about two-thirds of the dogs showed improvement in their symptoms, and the average survival time was about 15 months. Most dogs experienced only mild side effects, with no serious long-term issues noted. This suggests that IMRT can be an effective option for dogs with nasal tumors, helping them feel better and live longer.

People also search for: dog nasal tumor treatment · radiation therapy for dogs · nasal cancer in dogs survival rate

Abstract

Intensity-modulated radiation therapy (IMRT) is a valuable tool in human radiation oncology, but information on its use in veterinary medicine is lacking. In this study, 12 dogs with nasal tumors were treated with IMRT at a median radiation dose of 54 Gy. Patient survival times and frequency and severity of side effects on ocular structures, oral mucosa, and skin were recorded. Eight dogs (67%) had resolution of clinical signs during radiation therapy. Median overall survival time was 446 d with a 50% 1-year and a 25% 2-year survival rate. Minimal grade 2 or 3 acute skin toxicity, no grade 2 or 3 late skin toxicity, and no grade 2 or 3 toxicity to oral mucosa or the eye opposite the tumor were identified in the dogs treated with IMRT in this study. The ipsilateral eye could not be routinely spared due to its proximity to the tumor.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/20514254/