Peer-reviewed veterinary case report
Partial bladder removal outcomes for dogs with bladder cancer
By Marvel, S J et al.·Published in Veterinary and comparative oncology·2017·Department of Clinical Sciences, United States·View original on PubMed →
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Original publication title: Clinical outcome of partial cystectomy for transitional cell carcinoma of the canine bladder.
- Species:
- dog
Plain-English summary
A group of dogs with bladder cancer (transitional cell carcinoma) underwent surgery to remove part of their bladder, along with some receiving additional treatments like piroxicam, a pain reliever that can also help with cancer. The dogs that had the surgery and took piroxicam daily lived significantly longer, with a median survival time of about 772 days. This suggests that surgery combined with piroxicam can be more effective than just medical treatment alone for certain dogs with this type of cancer. If your dog has been diagnosed with bladder cancer, discussing surgical options with your vet may be beneficial.
People also search for: dog bladder cancer treatment · transitional cell carcinoma in dogs · piroxicam for dog cancer · dog bladder surgery recovery · how long can a dog live with bladder cancer
Abstract
Canine transitional cell carcinoma (TCC) of the bladder has historically been treated with a combination of chemotherapy, cyclooxygenase inhibitors and radiation therapy. While surgery has been used to treat TCC of the bladder, its efficacy has yet to be established. Thirty-seven client owned dogs that underwent partial cystectomy +/- various nonsurgical treatments for TCC were retrospectively evaluated. The overall median progression-free interval (PFI) was 235 days and the median survival time (ST) was 348 days. Prognostic factors identified on univariate analysis significant for ST were age, tumor location, full thickness excision and frequency of piroxicam administration. Prognostic factors significant for PFI were full thickness excision and frequency of piroxicam administration. The median ST with partial cystectomy and daily piroxicam therapy, with or without chemotherapy, was 772 days. Dogs with non-trigonal bladder TCC treated with full thickness partial cystectomy and daily piroxicam (+/- chemotherapy) may have improved outcome compared to dogs treated with medical therapy.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/28217972/