Peer-reviewed veterinary case report
Clinical Pharmacology in Donkeys and Mules.
- Journal:
- The Veterinary clinics of North America. Equine practice
- Year:
- 2019
- Authors:
- Mendoza, Francisco J et al.
- Affiliation:
- Department of Animal Medicine and Surgery · Spain
- Species:
- horse
Abstract
Donkeys and mules show several pharmacodynamic and pharmacokinetic idiosyncrasies that have to be fully considered by any clinician dealing with these species. Because they possess an increased metabolic rate and cellular water content compared with horses, higher doses (or shorter dosing intervals) are usually recommended for those drugs where pharmacologic studies have been performed. Nonetheless, owing to the lack of species-specific information, this assumption cannot be arbitrarily applied. Thus, when a drug protocol published for horses is extrapolated to a donkey or a mule, a close monitoring is required to detect any secondary effect or subdosing.
Find similar cases for your pet
PetCaseFinder finds other peer-reviewed reports of pets with the same symptoms, plus a plain-English summary of what was tried across them.
Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/31587974/