Peer-reviewed veterinary case report
Clinical presentation, diagnostic findings, prognostic factors, treatment and outcome in dogs with meningoencephalomyelitis of unknown origin: A review.
- Journal:
- Veterinary journal (London, England : 1997)
- Year:
- 2019
- Authors:
- Cornelis, I et al.
- Affiliation:
- Small Animal Department
- Species:
- dog
Plain-English summary
Meningoencephalomyelitis of unknown origin (MUO) is a serious condition in dogs that affects the brain and spinal cord, likely due to the immune system mistakenly attacking these areas. This review discusses how veterinarians can recognize the signs of MUO, what tests can help diagnose it, and the different treatment options that have been tried. Because MUO can be fatal if not treated, understanding which factors might predict a dog's outcome is very important. Overall, the review highlights the challenges in managing this condition and the need for better ways to help affected dogs.
Abstract
Meningoencephalomyelitis of unknown origin (MUO) encompasses a group of idiopathic, most likely immune mediated, inflammatory central nervous system diseases that cause clinical, diagnostic and treatment challenges to veterinary neurologists. Clinical criteria for obtaining this presumptive diagnosis are currently available, and multiple treatment protocols have previously been investigated in small (prospective or retrospective) case series. As this group of diseases is considered fatal if left untreated, the identification of clinically usable prognostic indices could be of great value. This review provides an overview of recent developments in the clinical presentation, diagnostic findings, possible prognostic factors, treatment and outcome in dogs diagnosed with MUO.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/30825893/