Peer-reviewed veterinary case report
Dog's eye inflammation from Brucella canis cleared with gentamicin
By Vinayak, Arathi et al.·Published in Journal of the American Veterinary Medical Association·2004·Department of Small Animal Medicine, United States·View original on PubMed →
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Original publication title: Clinical resolution of Brucella canis-induced ocular inflammation in a dog.
- Species:
- dog
Plain-English summary
A 2-year-old spayed female mixed-breed dog was suffering from recurring eye inflammation and bleeding for 8 months due to an infection called Brucella canis. Previous treatments with doxycycline and other medications didn’t work, but after starting a new treatment plan that included gentamicin, ciprofloxacin, and doxycycline, her eye inflammation improved significantly. The dog's test results showed that the infection was likely eliminated, and 35 months later, her eye condition remained resolved. This case highlights a successful approach to treating eye problems caused by this specific infection in dogs.
People also search for: dog eye inflammation treatment · Brucella canis infection in dogs · doxycycline for dog eye problems
Abstract
A 2-year-old spayed female mixed-breed dog was referred with an 8-month history of recurrent bilateral anterior uveitis and hyphema secondary to infection with Brucella canis. Treatment with doxycycline PO and atropine and prednisone acetate topically prior to referral had failed to resolve the ocular inflammation. Successful control of ocular inflammation was achieved after initiation of treatment with gentamicin SC and ciprofloxacin and doxycycline PO. The finite indirect fluorescent antibody (IFA) titer was reduced by half, and results of an agar gel immunodiffusion (AGID) test became negative after rifampin was added to the treatment protocol. Treatment with gentamicin was eventually discontinued because of evidence of renal toxicosis and cutaneous reactions to repeated injections. Thirty-five months after initial examination of the dog, results of the AGID test were still negative, the finite IFA titer was stable, and ocular inflammation had resolved, suggesting that the ocular infection may have been eliminated. To our knowledge, this represents the first report of the successful treatment of ocular inflammation caused by B canis infection in a dog.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/15198266/