Peer-reviewed veterinary case report
Testosterone treatment for urinary leaking in male dogs and side
By Palerme, Jean-Sébastien et al.·Published in Journal of the American Animal Hospital Association·2017·From Iowa State University College of Veterinary Medicine·View original on PubMed →
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Original publication title: Clinical Response and Side Effects Associated with Testosterone Cypionate for Urinary Incontinence in Male Dogs.
- Species:
- dog
Plain-English summary
Eight male dogs with urinary incontinence due to urethral sphincter mechanism incompetence (USMI) were treated with testosterone cypionate, an injection given every four weeks. Owners reported that three dogs showed a good to excellent improvement, one had a slight response, and four did not respond well at all. No side effects were noted during the treatment. For two of the dogs that improved, the owners decided to continue the therapy, suggesting that testosterone cypionate could be a safe option for managing urinary incontinence in male dogs.
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Abstract
Urethral sphincter mechanism incompetence (USMI) is reported much more seldom in male dogs than in female dogs. The few existing reports evaluating the efficacy of medical therapy in controlling USMI in males have demonstrated limited success. In this case series, we report the effect of testosterone cypionate, given at a median dose of 1.5 mg/kg intramuscularly every 4 wk, in eight male dogs with USMI. Response was evaluated through the review of medical records and telephone interviews with the clients. Based on owners' assessments, a good to excellent response was reported in three of eight dogs (38%), a slight response was reported in one of eight dogs (12%), and a poor response was reported in four of eight dogs (50%). Adverse effects were not reported, and benefit was judged sufficient to continue therapy in two cases. The results reported in this case series suggest that testosterone cypionate might be an effective and safe treatment option for male dogs with USMI.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/28792796/